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Pleiotropic effects of the carnitine pool Carnitine can be combined with fatty acid chains of different lengths to derive a variety of acylcarnitines, which are amphiphilic because they contain hydrophilic quaternary ammonium groups and hydrophobic carbon chains [5], and acylcarnitines of different chain lengths have diverse chemical structure and metabolic pathways, making them widely involved in pathophysiology

[DOI] [PubMed] [Google Scholar] Moore M.C., Werner U., Smith M.S., Farmer T.D., Cherrington A.D

Other longterm weight loss studies showed that most of the benefit on blood pressure by weight reduction is seen in the first 18 months of weight loss, after which BP rebounds back even with the continuation of weight loss [17, 18]